Analyse der Gehirninfektion bei Schlafkrankheit

 


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Some features of this site may not work without it. Analyse der Gehirninfektion bei Schlafkrankheit Frey, Claudia. Analyse der Gehirninfektion bei Schlafkr Day of Oral Examination: Parasit , Trypanosomen , Gehirn License: Publishing license excluding print on demand Show full item record Inhaltszusammenfassung: Diese Arbeit zeigt anhand von elektronenmikroskopischen Aufnahmen aus Rattengehirnen, wie Trypanosomen ins Gehirn gelangen und eine Infektion etablieren.

Die Kultivierungsversuche mit Liquor zeigen, dass die Trypanosomen nicht in der Lage sind, lange im Liquor zu überleben und relativ schnell in eine andere Gehirnregion gelangen müssen. Dieser Infektionsverlauf ist mit den Symptomen der Schlafkranken gut vereinbar: Zuerst entwickeln die Schlafkranken eine Plexitis, dann eine Meningitis und erst am Schluss ihrer Erkrankung eine Enzephalitis.

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